个人简历：

刘希玲，女，博士，副研究员，硕士生导师。2021年司法鉴定科学院优秀科技工作者；2021年司法鉴定科学研究院科学技术进步奖；2020年司法鉴定科学院青年科技论坛科技成果奖；2019年司法鉴定科学研究院科学技术进步奖；2018年司法鉴定科学院优秀论文奖；2018年入选“上海市人才发展基金”；2017年上海市科学技术进步奖一等奖；2015年入选“中国科学院青年创新促进会会员”；2014年赛诺菲-中科院上海生命科学研究院优秀青年人才奖；2012年中科院上海生命科学研究院计算生物学研究所第一作者奖；2010年法国里昂SMBE大会Postdoc Travel Award。曾担任国家自然科学基金评审专家，BMC Genomics、Genome Biology and Evolution、法医学杂志、中国司法鉴定杂志、Forensic Sciences Research审稿人、专业编辑，2021年受聘为Frontiers in Genetics审稿人。

主要研究方向：

复杂亲缘关系鉴定；人体表型分子鉴识。

主要承担科研项目：

1. 上海市自然科学基金青年基金项目，组蛋白修饰对人脑发育的调控机制研究，2013.10-2016.9。

2.中科院上海生科院优秀青年人才领域前沿项目，人脑发育过程中组蛋白修饰模式及作用，2013.8-2015.7。

3.国家自然科学基金青年科学基金项目，人脑发育过程中特异基因表达的表观遗传调控机制，2016.1-2018.12。

4.中央级科研院所社会公益研究资助项目，基于CNV的同卵双生子个体识别应用研究，2017.1-2019.12。

5.上海市技术标准专项项目，基于多组学技术识别同卵双生子的应用标准研究，2017. 8-2020.7。

6.国家重点研发计划子课题，复杂亲缘关系计算模型及其在心源性猝死鉴定中的应用研究，2018.7-2021.6。

7.国家自然科学基金面上项目，同卵双生子发育过程中的序列变异及其法医学应用研究，2019.1-2022.12。

8.中央级科研院所社会公益研究资助项目，基于复合遗传标记的祖孙关系鉴定研究，2021.1-2023.12。

代表性学术成果：

1.  Qiannan Xu^*, Ziwei Wang, Qianqian Kong, Xiaoxiao Wang, Ao Huang, Chengtao Li^#, Xiling Liu^#(共同通讯作者). Evaluating the effects of whole genome amplification strategies for amplifying trace DNA using capillary electrophoresis and massive parallel sequencing. Accepted by FSI Genetics. 2021.

2.  Qiannan Xu^*, Jiayi Zhang, Li Li, Chengtao Li^#, Xiling Liu^#(共同通讯作者). Evaluating the amplification efficiency of the MALBAC Single-cell DNA Kit for trace DNA. FSI Genetics Supplement Series. 2019. 7(1): 351-352.

3.  Jiayi Zhang^*, Qiannan Xu, Liqin Chen, Xiling Liu^#(共同通讯作者), Chengtao Li^#. Comparison of Three Different Pretreatment Methods for Blood RNA Extraction. FSI Genetics Supplement Series. 2019. 7(1): 329-330.

4.  Xiling Liu^*#(共同第一作者；共同通讯作者), Zhenmin Zhao^*, Qiannan Xu, Jiayi Zhang, Chengtao Li^#. Analysis of full- and half-siblings using a combined system of STR, InDel and SNP markers. FSI Genetics Supplement Series. 2019. 7(1): 349-350.

5.  Xiling Liu^*#(共同第一作者；共同通讯作者), Zhenmin Zhao^*, Qiannan Xu, Zheng Wang，Yingnan Bian, Suhua Zhang, Chengtao Li^#. Genome-wide copy number variation analysis in monozygotic twins. FSI Genetics Supplement Series. 2017. 6:e218-e220.

6.  Xiling Liu^*(共同第一作者), Fang Chen^*, Yong Niu^*, Yingnan Bian, Suhua Zhang, Ruxin Zhu, Chengtao Li. Population genetics of 30 insertion/deletion polymorphisms in Han Chinese population from Zhejiang Province. FSI Genetics. 2017. S1872-4973(17)30039-X.

7.  Xiling Liu^*(共同第一作者), Dingding Han^*, Mehmet Somel^*, Xi Jiang, Haiyang Hu, Patricia Guijarro, Ning Zhang, Amanda Mitchell, Tobias Halene, John J. Ely, Chet C. Sherwood, Patrick R. Hof, Zilong Qiu, Svante P??bo, Schahram Akbarian, Philipp Khaitovich. Disruption of an evolutionarily novel synaptic expression pattern in autism. PLoS Biology. 2016. 14(9): e1002558.

8.  Katarzyna Bozek, Yuning Wei, Zheng Yan, Xiling Liu, Jieyi Xiong, Masahiro Sugimoto, Masaru Tomita, Svante P??bo, Chet C. Sherwood, Patrick R. Hof, John J. Ely, Yan Li, Dirk Steinhauser, Lothar Willmitzer, Patrick Giavalisco, Philipp Khaitovich. Organization and Evolution of Brain Lipidome Revealed by Large-Scale Analysis of Human, Chimpanzee, Macaque, and Mouse Tissues. Neuron. 2015. 85(4): 695-702.

9.  Mehmet Somel, Rori Rohlfs, Xiling Liu. Transcriptomic insights into human brain evolution: acceleration, neutrality, heterochrony. Current Opinion in Genetics & Development. 2014. 29C:110-119.

10. Katarzyna Bozek, Yuning Wei, Zheng Yan, Xiling Liu, Jieyi Xiong, Masahiro Sugimoto, Masaru Tomita, Svante P??bo, Raik Pieszek, Chet C. Sherwood, Patrick R. Hof, John J. Ely, Dirk Steinhauser, Lothar Willmitzer, Josep Call, Patrick Giavalisco, Philipp Khaitovich. Exceptional evolutionary divergence of human muscle and brain metabolomes parallels human cognitive and physical uniqueness. PLoS Biology. 2014.12(5): e1001871.

11. Mehmet Somel, Xiling Liu, Philipp Khaitovich. Human brain evolution: transcripts, metabolites and their regulators. Nature Reviews Neuroscience. 2013. 14(2): 112-127.

12. Pavel Mazin^*, Jieyi Xiong^*, Xiling Liu^*(共同第一作者), Zheng Yan, Liu He, Mehmet Somel, Yuan Yuan, Na Li, Yuhui Hu, Ning Fu, Zhibin Ning, Rong Zeng, Wei Chen, Mikhail Gelfand, Philipp Khaitovich. Widespread splicing changes in human brain development and aging. Molecular Systems Biology. 2013. 9: 633.

13. Xiling Liu^*(共同第一作者), Mehmet Somel^*, Lin Tang^*, Zheng Yan, Xi Jiang, Song Guo, Yuan Yuan, Liu He, Anna Oleksiak, Yan Zhang, Na Li, Yuhui Hu, Wei Chen, Zilong Qiu, Svante P??bo, Philipp Khaitovich. Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques. Genome Research. 2012. 22(4), 611-622.

14. Mehmet Somel^*, Xiling Liu^*(共同第一作者), Lin Tang, Zheng Yan, Hai Yang Hu, Song Guo, Xi Jiang, Xiaoyu Zhang, Guo Hua Xu, Gangcai Xie, Na Li, Yuhui Hu, Wei Chen, Svante P??bo, Philipp Khaitovich. MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates. PLoS Biology. 2011. 9(12): e1001214.

15. Xing Fu^*, Patrick Giavalisco^*, Xiling Liu^*(共同第一作者), Gareth Catchpole, Ning Fu, Zhi-Bin Ning, Song Guo, Zheng Yan, Mehmet Somel, Svante P??bo, Rong Zeng, Lothar Willmitzer, Philipp Khaitovich. Rapid metabolic evolution in human prefrontal cortex. PNAS. 2011. 108: 6181-6186.

联系邮箱: liuxl@ssfjd.cn; xlliu323@gmail.com